Reproducible Topical Staphylococcal Infection in Rats1

Staphylococcal infection in hospitals.

Recurrent staphylococcal infection in families.

This controlled double-blind study examined the efficacy of a single large inoculum of Staphylococcus aureus 502A in interrupting intrafamilial spread of recurrent staphylococcal abscesses. Forty families were enrolled in the study and 32 completed six months of follow-up care. All participants were first treated with oral oxacillin sodium or dicloxacillin sodium, twice daily hexachlorophene sh...

Staphylococcal Infection and Infertility

Staphylococcus sp. is not only a commensal bacterium but also a major human pathogen that causes a wide range of clinical infections, such as skin and soft tissue infection, pleuropulmonary and osteoarticular infection, and endocarditis as well as lifethreatening systemic infections. More evidence is currently emerging to show that Staphylococcus, particularly Staphylococcus aureus, can coloniz...

A Reproducible Implant Infection Model in Rabbits

INTRODUCTION: Orthopaedic prostheses implantation is an invasive surgical procedure, with an increased risk for post-operative infections. Since the life span and quality of these implants is improving and more prostheses are implanted every year, the incidence of post-operative infections will increase. Most implants are based on titanium or nickel-chromemolybdenum alloys, while their overall ...

Anti-staphylococcal activity of indolmycin, a potential topical agent for control of staphylococcal infections.

OBJECTIVES We sought to investigate the anti-staphylococcal activity of indolmycin, with particular emphasis on comparing its activity with fusidic acid and mupirocin. METHODS Established procedures were used to examine the activity of indolmycin against a range of clinical isolates, including strains resistant to fusidic acid and mupirocin. Indolmycin-resistant mutants were recovered and cha...